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In part this was because a set of experiments conducted in dogs between 1939 and 1940 cast doubt about the existence of incretin

However if the recommended dose of the drug does not help in improving the condition then one should consult a doctor

Over time, the rubber septum of the injection vial can allow bacterial infiltration, and the preservative system in the formulation degrades

Even though GLP-1 medications may increase heart rate slightly, theres no evidence that they increase the risk of arrhythmias (irregular heart rhythms)

Such use may be motivated by personal preferences, GI tolerability, costs, and drug shortages