semaglutide make you throw up Nausea: Why It Happens and How to Manage Does Semaglutide Injection Cause Nausea?

The animal experiment was approved by the Animal Ethics Committee of Tongji Medical College, Huazhong University of Science and Technology (HUST) and its IACUC number is S2095

Oral semaglutide formulations require intact stomach acidity for proper absorption and may show reduced effectiveness when combined with omeprazole

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doi: 10.1136/bmjopen-2011-000494

One probable interpretation is that transport of molecules across the BBB is highly controlled and the ingestion of the abnormally high doses of drug may affect this