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Semaglutide is commonly prescribed for the treatment of type 2 diabetes, as it helps to regulate blood sugar levels by enhancing insulin secretion, reducing glucagon release and slowing gastric emptying

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Both structural and functional analyses revealed Cagris non-selective activation of Gs signaling pathways through CTR and AMY1R

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Confirmatory secondary end points included change in 6-minute walk distance, a hierarchical composite end point (death, HF events, and change in KCCQ-CSS and 6-minute walk distance) and change in C-reactive protein