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Obes Rev 11(7):531547

While these medications have similar goals, some differences between them are worth noting

For example, persistent gastrointestinal symptoms leading to dehydration or a noticeable drop in eGFR or increase in UACR should prompt a temporary pause in medication

Each represents a potential litigation target or licensing negotiation point as the base composition of matter patents expire and biosimilar/generic developers assess freedom to operate

Several studies have shown that GLP-1 agonists can improve menstrual cyclicity, reduce hyperandrogenism, and increase ovulation rates in women with PCOS
