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[15] The lesson: Slow and steady wins the race (or at least ties, albeit with far less nausea)

Our findings broadly support the advice to discontinue GLP-1 agonists and SGLT2 inhibitors during pregnancy and lactation, and also support the ongoing registration of pregnancy outcomes in pharmacological databases since the amount of available data is scarce and mostly limited to animal studies

Benefits Beyond Weight Loss Compounded semaglutide not only helps with weight loss but also plays a significant role in managing blood sugar levels

Suppressed glucagon secretion By binding receptors on -cells, it inhibits glucagon release during hyperglycemia

Furthermore, the TGA-approved dual glucose-dependent insulinotropic polypeptide/GLP-1 receptor agonist tirzepatide has some evidence of renal benefit, based on a post-hoc analysis of the SURPASS-4 trial findings