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Pietrzak, The physical and mental health burden of obesity in U.S
GIP and the intramural intestinal autonomous nervous system have been suggested as signaling pathways [323]

FDA-approved medications for these conditions have been scarce

Clinical trials show average weight reductions of 1520% with lifestyle changes, establishing it as one of the leading weight loss medications
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J Clin Invest 1987;79:616-9.ArticlePubMedPMC 11
