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GLP-1 may affect systemic energy metabolism by regulating adipocyte development, accelerating plasma clearance of glucose and triacylglycerol-derived fatty acids, improving insulin signaling, and stimulating thermogenesis in brown adipose tissue (BAT) [40-45]

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This mechanism supports effective blood sugar regulation while minimizing the risk of hypoglycemia

Lower systemic inflammation : Obesity-driven inflammation contributes to airway swelling

Additionally, aspiration risk has been raised as a concern primarily in perioperative settings due to delayed gastric emptying, leading to recent multi-society anesthesia guidelines addressing GLP-1 receptor agonist management before procedures

The type of vision loss associated with Ozempic use is called NAION (nonarteritic anterior ischemic optic neuropathy)