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Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are highly effective for body weight reduction, there remains a critical unmet need for complementary strategies that drive selective fat loss and sustain long-term weight reduction

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Diese Behandlungen sind zwar wirksam, erfordern jedoch eine sorgfltige berwachung, insbesondere bei nicht-diabetischen Patienten, da Nebenwirkungen auftreten knnen

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We hypothesized that the central regions of highest Glp-1r gene activity are essential in mediating responses to drugs of abuse