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This newly charted pathway - separate from previously described mechanisms that broadly affect appetite - could be an avenue by which GLP-1s treat other dysfunctions in reward processing, such as substance use disorder
With over 50% of GLP-1 users discontinuing due to cost and 36% due to side effects, Nooms low and slow titration strategy could offer a more sustainable path to weight loss

Anyone considering using or just starting a GLP-1 medication
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The most interesting reason to pursue glucagon agonism in a multi-receptor agonist is the possibility that you could alter hepatic liver metabolism and potentially decrease fatty acid accumulation and hypertriglyceridemia, said David A