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Why do some people not respond to semaglutide in the UK

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The collagen matrix that was organized to support a larger body surface area doesn't contract quickly enough, leaving loose, sagging skin

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There is limited evidence that patients who fail to respond to tirzepatide will necessarily respond better to other incretin-based therapies, but individual variation may result in differential responses

The two GLP-1 receptor agonists covered in this guide have common side effects nausea, diarrhea, and vomiting but in the 2021 study weve referenced, semaglutide exhibited up to a 5% lower risk of nausea, 4% of diarrhea, and 2% of vomiting.3 Its lower side effect risk compared to tirzepatide is slight but clear