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Clinical trial meta-analyses show a statistically significant association between semaglutide (and GLP-1 agonists broadly) and increased DVT risk
However, it is essential to interpret this result with caution, as the EBGM05 for GLP-1RA-associated suicide/self-injury in children was lower than 2, suggesting a lack of robust signal strength
Accessed October 9, 2025
However, there was no significant improvement in fibrosis stage by semaglutide therapy
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[Google Scholar] 78.Trimarco V., et al
