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What the Clinical Data Actually Shows Both medications have demonstrated significant effectiveness in clinical trials
With the matched group on semaglutide, 28 reported gastroparesis.[ref][ref] Diabetic retinopathy: Two clinical trials in people with diabetes linked GLP-1 RA drugs to an increased risk of diabetic retinopathy, while other studies show that the drugs were not associated with the eye disease

PLoS One 7 , e36965 (2012)

During optimization and maintenance (weeks 11 onward), your eating pattern will have naturally shifted to smaller portions and less frequent meals

Clinical studies have shown that both medications can result in significant weight loss for individuals with type 2 diabetes

Slowed gastric emptying lets food sit longer in the stomach where bacteria produce hydrogen sulfide gas, while undigested fats and bile move into the colon and trigger looser stools
