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Parenteral delivery systems, including intramuscular, intravenous, and subcutaneous injections, are highly preferred for their rapid onset of action, precise dosing, and high bioavailability

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SURMOUNT-1 results (72 weeks, adults with obesity): 5 mg dose: approximately 15% body weight loss 10 mg dose: 19.5% body weight loss 15 mg dose: 22.5% body weight loss Placebo: 3.1% body weight loss At the 15 mg maximum dose, the average participant lost about 52 pounds over 72 weeks

The kidney benefits of GLP1-RA include reduction in macroalbuminuria, which may be driven in part by reductions in blood pressure and A1c with these agents
