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Mitigating Side Effects Several strategies have proven effective for managing adverse events: Starting with lower doses (e.g., 0.5 mg) rather than higher doses Implementing gradual dose escalation with adequate time between increases Maintaining patients at current doses longer when side effects emerge Monitoring and providing supportive care for gastrointestinal symptoms[8] These approaches can significantly improve tolerability and adherence to the medication regimen

Reality check: this is still preclinical

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The line chart shows us that from 2020 onward, the unit cost trend for behavioral health spiked to 2023 from about $100 to $125m and that behavioral health claims as a percent of all medical claims more than doubled between 2018 to the third quarter of 2023