glp-1 drugs Medications Show Promise as First Drug Therapy for Sleep Apnea GLP-1 Agonists - What is

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Peptides 18 , 625632 (1997)

As the role of obesity in diseases ranging form Prader-Willi syndrome to cardiovascular disease becomes increasingly clear, the potential impact of GLP-1 receptor agonists extends far beyond weight loss alone

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4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 Exenatide and lixisenatide are analogues of exendin4 (a peptide agonist of the GLP1 receptor, obtained from the Gila monster) 13

5 Mechanistically, exercise-induced interleukin-6 (IL-6) appears to stimulate GLP-1 secretion from intestinal L-cells and pancreatic -cells in experimental models, which may contribute to improved appetite regulation and insulin secretion during and after exercise