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These benefits include reducing neuroinflammation, improving neuronal energy homeostasis, and limiting neurodegenerative progression ( Potential mechanisms by which GLP-1RAs enhance cognition in T2DM patients include attenuation of oxidative stress, suppression of neuroinflammation, inhibition of apoptosis, reduction or prevention of A accumulation, and mitigation of tau aggregation ( These pharmacological advances have reshaped the management of metabolic diseases, improving glycemic control, weight reduction, and cardiovascular outcomes

[61] confirmed the efficacy of semaglutide in determining an improvement in hepatic cytolysis indices with a dose-dependent effect

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Strategies include starting with a low dose and gradually increasing it, making dietary changes, staying hydrated, and in some cases, prescribing anti-nausea medications

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