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The endogenous GLP-1 hormone is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4), resulting in a half-life of less than 5 min in the circulation (2, 3)

Sleep 22 , 901912 (1999)

Without conscious effort and instructions to eat until satisfied, the participants in the Hops group reduced their food intake by 14.3% following a 24 hour fast (compared to placebo) [1]
