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Tirzepatide is a dual GIP/GLP-1 receptor agonist studied for its relationship to incretin signaling, glucose-response pathways, appetite-regulation models, and metabolic research systems

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SURPASS-CVOT trial: For patients with high-risk type 2 diabetes, the effect of tirzepatide, a dual agonist of the GLP-1 and glucose-dependent insulinotropic polypeptide receptors, on cardiovascular outcomes is uncertain