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Olubunmi Oladunjoye discusses GLP-1 medications for weight management, including their rise in popularity and possible side effects.

Glucagon-like peptide 1 receptor agonists and combination medications (GLP-1s) are shifting the treatment landscape for obesity

This is evidenced by up-regulation of glycolytic enzyme expression, increased rates of glucose uptake and consumption, as well as augmented ATP content, insulin secretion and glycolytic flux after removal of Exendin-4

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But she also acknowledges seeing patients benefit from low maintenance doseswe just don't have systematic evidence on who, when, and how