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References Van Zuylen ML, et al
Insuficiencia cardiaca con fraccin de eyeccin preservada (HFpEF) asociada a obesidad: ensayos STEP-HFpEF (con y sin DM2) demostraron mejora de sntomas, limitacin fsica y capacidad de ejercicio , adems de ms prdida de peso, en 52 semanas (7)

doi: 10.1016/J.CMET.2017.04.009
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Estrogen therapy, particularly through pellet treatments, tends to be more effective and well-tolerated by both women and men
