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Two major neuronal populations present in the arcuate nucleus control caloric intake and energy expenditure: one population co-expresses orexigenic agouti-related peptide (AgRP) and neuropeptide Y and the other expresses the anorexigenic anorectic neuropeptides proopiomelanocortin and cocaine- and amphetamine-regulated transcript (POMC/CART)

We break down the key differences in mechanism, evidence base, side effects, and who each one is actually relevant for.

Learn more about trends in GLP-1 perceptions and coverage strategies Obesity is one of the largest public health concerns in the United States, and for many people, lifestyle modification alone does not produce sufficient weight loss