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An additional translational concern is that chronic inhibition of GHSR signalling may impair counter-regulatory responses during prolonged fasting, potentially increasing vulnerability to hypoglycaemia in susceptible individuals

The presence of collaterals is likely protective against developing VSR and reducing size of infarct

Consult your doctor about your health

Duration depends on your individual metabolic response, baseline health markers, and provider assessment

In patients receiving SEM as the third-line therapy (add-on to MET + TZD or MET + SU), treatment with either dose of SEM for 30 weeks to 56 weeks was associated with greater glycemic control, compared with SIT, EXE, or IG (Table 20)

Regular follow-up appointments are essential for monitoring treatment response, managing side effects, and assessing ongoing suitability