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Declarations Funding This study was sponsored by Novo Nordisk A/S
Drug Interactions: Bupropion inhibits Cyp 2D6, although it is actually metabolized primarily by Cyt 2B6

Long-term metformin use and vitamin B12 deficiency in the diabetes prevention program outcomes study

Nat Med 2024

Prompted by this evidence, we reviewed the literature on endocrine features in PWS to evaluate whether a genotype-phenotype correlation can be established

Persistent sleep disturbances beyond 46 weeks or severe symptoms warrant medical review and possible dose adjustment
