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Description
Cold Storage and Access Challenges: The Final Hurdle in GLP-1 Availability While the FDA may determine that the national supply of tirzepatide and other GLP-1 medications is sufficient to meet market demand, the reality for patients often tells a different story

Access is still an issue for these effective medications. Clare Thompson, MD, a general practitioner who leads weight management services at the Cadogan Clinic in London, agrees

A recent real-world study from Virta Health found that individuals with type 2 diabetes who discontinued GLP-1 therapy while continuing a ketogenic or low-carb diet maintained their weight loss over 12 months, with more than 70% sustaining at least 5% weight loss
In the landmark Phase 3 VESALIUS-CV trial (12,000+ patients), adding Repatha to standard cholesterol-lowering therapy significantly reduced the risk of: Heart attacks Ischemic strokes Coronary deaths This makes Repatha the first PCSK9 inhibitor to demonstrate preventive benefits before heart disease strikes a true paradigm shift in cardiovascular care

Kasiske BL, Snyder JJ, Gilbertson D, Matas AJ

No obstante, la hipertensin no fue un desenlace en los estudios LEAD por lo que no se discrimin el uso de medicamentos antihipertensivos concomitantes
