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Glucagon-like peptide-1 receptor agonists (#GLP1s) are associated with a reduced overall cancer risk in adults with obesity, lowering the risk for endometrial, ovarian, and meningioma cancers, while potentially increasing the risk for kidney cancer

The 39 amino acid sequence of tirzepatide shares similarity with that of GIP, GLP-1 and exendin-4 and is characterized by an acyl chain attached to the lysine residue at position 20 contributing to albumin binding and half-life extension to 5 days [41]

Diabetes Care 45(4):909918

Some real-world cohorts and pooled analyses report greater weight loss among women treated with GLP-1 RAs than among men, though findings are not entirely consistent, and effect sizes vary by agent and population studied (Rivera et al., 2024

There is some concern that women may be underdiagnosed because of different symptoms