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Abstract The development oftirzepatide, a first in class dual glucose dependent insulinotropic polypeptide andglucagon like peptide 1 receptor agonist, represents a potentially transformative advance in the management oftype 2 diabetesandobesity

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Glucagon-like peptide-1(736)amide (GLP-1) is a secreted peptide that acts as a key determinant of blood glucose homeostasis by virtue of its abilities to slow gastric emptying, to enhance pancreatic insulin secretion, and to suppress pancreatic ...