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With several mechanisms, modalities, clinical needs, and routes of administration in development, the landscape is promising to become much more complex
Our findings revealed EC 50 values of 3.97 nM and 2.43 nM for GLP-1R internalization mediated by GEP44 and Ex-4, respectively, and EC 50 s of 1.59 nM and 7.13 nM for GEP44 and Ex-4, respectively, for -arrestin-2 recruitment
(U.S.) GSK plc (U.K.) Lupin Limited (India) Sun Pharmaceutical Industries Ltd
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Metabolic profiling revealed substantial decreases in blood glucose, plasma insulin, and glucagon in DIO mice receiving G49 treatment (Fig
N Engl J Med (2017) 377:122839
