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Compared with SGLT-2 inhibitor use, GLP-1 receptor agonist use was not associated with an increased risk of pulmonary aspiration (pooled risk ratio 0.98, 95% CI 0.73 to 1.31), although it was associated with a higher risk for discontinuation of endoscopy (1.99, 1.56 to 2.53)

It is often associated with the use of sodium-glucose cotransporter-2 (SGLT2) inhibitors, but can also occur in other settings such as fasting, illness, or alcohol abuse

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But if the prevention trials confirm what the observational data suggests, this class of drugs could change dementia care more than anything we've seen in decades