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In humans similar results were also obtained where the acute treatment of subjects with T2DM with dapagliflozin significantly improved systemic endothelial function and reduced both renal resistive index and aortic stiffness (56)

Cardiac structural and functional features in patients with type 2 diabetes mellitus and heart failure with preserved ejection fraction: a study based on propensity score matching

Some individuals find that they need to titrate up to the maximum dose of a given GLP-1 drug fairly quickly, while others are able to make progress on a lower dose for an extended period

Despite this heterogeneity, the current review needed to include more in discussing how it might impact generalizability

Kaitlin Sullivan Author Joseph Bennington-Castro Author Joseph Bennington-Castro is a science writer based in Hawaii
