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Look AR, Wing RR

The included studies on exendin-4 exposure were all performed in mouse models ( In rat, mouse and rabbit models without systemic inflammation, the other GLP1-receptor agonists (except exendin-4), dose dependently caused reduced fetal weight and/or growth, retardation of ossification, irregular ossification, and/or skeletal variants such as wavy ribs ( Table 1 )

Metformin is an insulin sensitizer that helps the body use existing insulin more effectively, while Ozempic is a hormone mimic that promotes new insulin secretion

Bacteriostatic water (containing 0.9% benzyl alcohol as a preservative) provides antimicrobial protection that sterile water does not

Because the health benefits of obesity treatment generally outweigh these temporary challenges, both proactive prevention strategies and effective support are crucial during periods of therapy adjustment

PMCID: PMC9224931