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Description
It actually appears to blunt GIP responsiveness in that population

Currently available biomarkers do not outperform serum ALT in identifying patients with NASH, which has poor sensitivity ( 3) and any amount of fibrosis, focus has shifted toward trials with fibrosis as the primary indicator of efficacy, as fibrosis is the histologic feature of NASH most clearly linked to risk of decompensation or liver-related events

2019;181:R21134

It typically occurs secondarily due to dehydration from gastrointestinal side effects such as nausea, vomiting, and diarrhoea, which are common, particularly during treatment initiation and dose escalation

Research shows that abdominal fat is the most dangerous location for fat deposition

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Bu H, Li L, Li X, Guo J
