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Description
While SUSTAIN-6 and REWIND trials examined GLP-1 RA in diabetics with different cardiovascular risk profile, The Harmony Outcomes study enrolled patients with T2D and established atherosclerotic cardiovascular disease (ASCVD)

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If fasting guidelines are meant to minimize residual gastric contents then the clear guidance would be to have these patients undergo prolonged fasting from solid food
Key Takeaway: GLP-1s dont directly cause acid reflux, but they create digestive conditions where reflux is more likely without proper nutrition support

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Novo Nordisk Internet

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