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Diarrhea with semaglutide is typically related to changes in bile acid metabolism and altered gut microbiome composition rather than the gastric emptying changes that cause nausea and constipation

Lillys tirzepatide, which may beat semaglutide 3-to-1 in terms of supporting weight loss goals according to early data released last year, is the subject of about one-third as many trials

Semaglutide, also known by the brand names Wegovy and Ozempic, is a glucagon-like peptide-1 (GLP-1) receptor agonist used to lower blood sugar levels, weight loss, and to lower the risk of heart attack, stroke, or death in patients with type 2 diabetes, obesity, and heart disease

Overactive Thyroid (hyperthyroidism)
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