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GLP-1R-mediated dopaminergic modulation may vary by drug class: in alcohol models, suppression of dopamine release is coupled with reduced locomotor sensitization [7,24], whereas in psychostimulant paradigms, GLP-1R activation primarily blunts drug-induced dopamine overflow without abolishing baseline dopaminergic tone [10]

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Funding information National Institutes of Health, Grant/Award Numbers: R01 DK119169, DK1191305830 DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request