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Clinical trials have shown promising results, with participants achieving weight loss of 15 to 20 percent over a period of 72 weeks

10.1021/acs.jmedchem.0c01576 [DOI] [PubMed] [Google Scholar] 16.Kurtzhals P, Havelund S, Jonassen I, et al

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Maintenance dosing means using only as much medicine as you need to hold results stable, not to shed any additional weight

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But berberines glucose-lowering is glucose-dependent, meaning it tends to work harder under hyperglycemic conditions
