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Treatment of SAD is started in the fall before depressive symptoms begin and continued throughout the winter until early spring

J Clin Endocrinol Metab 94(6):18431852

Circulation 136:18401850 Malhotra A, Grunstein RR, Fietze I et al (2024) Tirzepatide for the treatment of obstructive sleep apnea and obesity

Short-term studies might only capture the initial increase, while longer-term research is needed to understand potential adaptations or the chronic impact of a slightly elevated heart rate