glp-1 receptor agonist and dpp-4 inhibitor combination contraindicated Frontiers The mechanism of action of
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This variability restricted the possibility of conducting a meta-analysis and emphasized the need for standardized protocols in future research

doi: 10.1016/S0140-6736(19)31149-3

DPP4 consists mainly of three domains based on their binding sites (Figure 5)
GLP-1 receptor activation modulates appetite- and reward-related brain areas in humans
Mol Endocrinol 25: 2134-2143, 2011

Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake
