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Funding This study was supported by the Natural Science Foundation Project of Hunan province (2023JJ40917 and 2025JJ50624) and the Changsha Natural Science Foundation (kq2403192)

These drugs are indicated for patients who are treated with intermediate or long-acting GS taken twice a day or more [20,21]

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target is at least greater than 7% Overweight/obesity with baseline BMI ideally 25-30% +range Duration of diabetes does not affect parameters, but is usually used in patients when Metformin has proved ineffective/inadequate

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Private insurance can also cover a sizable portion of Zepbound and Wegovy, though prior authorization remains a requirement