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To unlock wider and more equitable access to novel obesity treatments, however, positive cardiovascular outcomes data will be absolutely critical to demonstrate substantial cost-savings for health systems from medication-assisted weight loss by avoiding downstream complications from obesity-related comorbidities

Both GLP-1 and GLP-1/GIP receptor agonists have different mechanisms and dose-response profiles

But the core molecule is now public property in most of the world, and the $26 billion business built on it will look very different by 2033

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