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Previous studies on PanNETs, specifically insulinomas, have demonstrated a relationship between GLP- 1R expression and prognosis, indicating that the lack of GLP- 1R expression is associated with poor prognosis [25]
GLP1 receptor agonist liraglutide is an effective therapeutic option for perioperative glycemic control in type 2 diabetes within Enhanced Recovery after Surgery (ERAS) protocols

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Tirzepatide is a synthetic peptide belonging to the class of dual incretin receptor agonists, designed to interact with both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor [1]

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