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Bertilsson, G

One sign of this is that research into using GLP-1s to treat still more conditions has exploded

These results suggest that the uptake of GLP-1RAs into the brain via tanycytes is important for their anti-obesity effects

doi: 10.2337/db13-0227

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5 Market outlook Eli Lillys oral non-peptide GLP-1RA orforglipron is advancing through the ACHIEVE Phase III program, with Lilly signaling regulatory submissions for obesity in 2025 and type 2 diabetes in 2026, following positive results from both Phase 2 obesity (GZGI) and Phase 3 T2DM (ACHIEVE-1) trials