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[DOI] [PubMed] [Google Scholar] [110].Bigal ME, Kurth T, Santanello N, Buse D, Golden W, Robbins M, et al

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In PCOS-related trials, even with low starting doses and gradual titration, discontinuation rates of approximately 5%15% are frequently observed (125, 128)

Reduced appetite at the starting dose means you may be eating significantly less without realizing it

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