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This often relates to reduced calorie intake rather than a direct medication effect

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Reported Side Effects (Phase 3 TRIUMPH-4 Data) Dysesthesia: The New Safety Signal Dysesthesia is an abnormal sense of touch where normal sensations feel unusual, uncomfortable, or mildly painful

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All of this matters because the brain, as we now know, has its own GLP-1 system, parallel to and largely separate from whatever is going on in the gut

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