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That research, published in JAMA Network Open , found that GLP-1 treatment plus exercise was the most effective strategy for weight loss and maintaining bone health

The GI consequences are severe

This becomes especially important during early treatment stages, when appetite and dietary habits may change.Read our guide on hydration while using Wegovy for more practical tips on maintaining optimal fluid levels during treatment

However, lower doses may be sufficient depending on individual response

Clinically, these reductions in physiological drive may provide a window of opportunity in which behavioral strategies such as stimulus control, self-monitoring, and structured eating routines may be adopted more consistently

So in certain populations we've seen a reduction in cardiovascular events, improved lipids and blood pressure profiles, and I'll talk a little bit more about that later on in the episode