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(2019) 317:E55972

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However, the anatomic distribution of the L-cells (highest number in distal gut) and the rapid increase in postprandial circulating GLP-1 (35) that occurs before nutrients reach the distal gut (8, 63) is evidence supportive of neural, endocrine and/or paracrine mechanisms being more critical to nutrient-induced increases in circulating GLP-1 (164)

Recent research suggests GLP-1 receptor expression varies across the gastrointestinal tract, with highest concentrations in the colon

Taking your birth control pill at a consistent time daily, separate from food, may optimize absorption

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