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This narrative reviewaims to analyzecurrent findings on the beneficial and adverse ocular effects of GLP-1RAsuse, highlighting studies that elucidate the harmful causes, such as retinal microvascular dysregulation, inflammatory modulation, oxidative stress,osmotic dysregulation from sorbitol accumulation,and metabolic shifts

Compounded semaglutide is made by a licensed compounding pharmacy in small quantities to meet the specific needs of a patient

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The analysis showed significantly greater WL in the GLP-1RAs group compared to placebo (SMD=0.82, 95% CI 0.23 to 1.42)
