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In contrast, both gut-selective and systemic inhibition of DPP-4 activity increased GLP-1 and lowered TG excursions in HFD-fed Dpp4 Gut/ mice (Figure 8)

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Other factors, like side effects and costs, should also be considered

By week 812, this symptom typically disappears entirely without any intervention

doi: 10.1016/j.numecd.2007.08.002