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"GLP-1/GIP/glucagon receptor tri-agonism: the emerging paradigm in obesity pharmacotherapy." Endocrinology and Metabolism

While semaglutide can cause nausea, vomiting, diarrhea, constipation, indigestion, and abdominal pain, these symptoms are generally manageable

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Questions to Ask Your Clinician Before or During Treatment Do you have a history of clotting or a family history of thrombophilia

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The findings confirm its cardiovascular safety and manageable GI side effects, reinforcing its role in metabolic disease management