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Some evidence suggests fibre may support gut bacteria, which could potentially influence appetite regulation, though research in this area is still emerging

The same applies to the elderly with weakened immune systems

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The most durable results come when pharmacological support is embedded within a broader lifestyle framework: resistance training to provide anabolic stimulus and maintain insulin sensitivity, protein sufficiency to support muscle protein synthesis, sleep optimization to preserve the nocturnal testosterone pulses that drive morning levels, and metabolic health management to reduce aromatase activity driven by visceral fat

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