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Half-life extending moieties may also affect the biodistribution of the polypeptide conjugate

Paradoxically, in pancreas-specific Gpx4 knockout KC models or under high-iron diet conditions, ferroptosis instead facilitated tumorigenesis (140)

Patients with pancreatitis have a greater than twofold higher lifetime risk of developing new onset diabetes than individuals in the general population without a history of pancreatitis

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These stapled peptides exhibited helicity in a pure phosphate buffer and various solvents, including TFE, methanol, and a combination of acetonitrile and buffer